Time for initiation of nutritional support was 2.5 ± 1.5 days. In total, 34 patients were included and 15 patients (age: 57.6 ± 12.8 years Simplified Acute Physiology Score II: 52 ± 11) were eligible for final analysis. The main criterion was the evolution of the energy deficit (dE) from D1 to D6. Metabolic data were collected using the COSMED Q-NRG + ® calorimeter: carbon dioxide production (VCO2), oxygen consumption (VO2), resting energy expenditure (REE), respiratory quotient (RQ) and the rate of substrate utilization (proteins, lipids, and carbohydrates). Prospective observational pilot study including ventilated adult patients with septic shock admitted in a surgical intensive care unit (ICU). The objective of this study was to describe its evolution using indirect calorimetry. Energy metabolism (energy deficit, substrate consumption) in the early phase of septic shock is not clearly understood.
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